Tert-Butylamine → HCID 67214944, compound

HRID 2421518Notes

Reaction equation

[CH3:1][S:2][CH:3]([O:7][C:8]1[CH:13]=[C:12]([CH3:14])[C:11]([Br:15])=[C:10]([CH3:16])[CH:9]=1)[C:4]([OH:6])=O.[C:17]([NH2:21])([CH3:20])([CH3:19])[CH3:18]>>[Br:15][C:11]1[C:12]([CH3:14])=[CH:13][C:8]([O:7][CH:3]([S:2][CH3:1])[C:4]([NH:21][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:6])=[CH:9][C:10]=1[CH3:16]

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 67214590HCID 67214590, compound

Product 1

HCID 67214944HCID 67214944, compound

Procedure

In a similar procedure to Stage 2 of Example 1, 2-methylthio-2(4-bromo-3,5-dimethylphenoxy)acetic acid was condensed with tert-butylamine to give 2-(4-bromo-3,5-dimethylphenoxy)-2-methylthio-N-(2-methyl-prop-2-yl)acetamide as a colourless solid, m.p. 123-125° C.

Sources & evidence

ORD record: ord-17a44cb35c904d00a458fb947a1cb8d6
Source dataset: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07956188B2

Reaction notes

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