Tert-Butylamine → HCID 67213892, compound

HRID 2421527Notes

Reaction equation

[I:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([O:12][CH:13]([S:17][CH3:18])[C:14]([OH:16])=O)=[CH:7][CH:6]=2.[C:19]([NH2:23])([CH3:22])([CH3:21])[CH3:20]>>[C:19]([NH:23][C:14](=[O:16])[CH:13]([O:12][C:8]1[CH:9]=[C:10]2[C:5](=[CH:6][CH:7]=1)[N:4]=[CH:3][C:2]([I:1])=[CH:11]2)[S:17][CH3:18])([CH3:22])([CH3:21])[CH3:20]

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 66718068(3-Iodo-quinolin-6-yloxy)-methylsulfanyl-acetic acid

Product 1

HCID 67213892HCID 67213892, compound

Procedure

In a similar procedure to Stage 2 of Example 1, (3-iodo-quinolin-6-yloxy)-methylsulfanyl-acetic acid was condensed with t-butylamine to give N-tert-butyl-2-(3-iodo-quinolin-6-yloxy)-2-methylsulfanyl-acetamide as a white solid (MH+ 431).

Sources & evidence

ORD record: ord-a70d7bd9f3df4349ba67bcc4e5df030a
Source dataset: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07956188B2

Reaction notes

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