Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2421529Generated: November 2, 2026

Ethyl 2-chloro-2-(methylsulfanyl)acetate → (3-Bromo-8-fluoro-quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl ester

https://huagongshe.com/reaction/2421529

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloro-2-(methylsulfanyl)acetateHCID 10877535—
Reactant3-Bromo-8-fluoro-6-quinolinolHCID 67214347—
Product(3-Bromo-8-fluoro-quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl esterHCID 67213833—

Reaction Steps

In a similar procedure to Stage 2, Step 1 of Example 5, 3-bromo-8-fluoro-quinolin-6-ol was reacted with chloro-methylsulfanyl-acetic acid ethyl ester to give (3-Bromo-8-fluoro-quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07956188B2
Source datasetuspto-grants-2011_06
ORD IDord-871a4f090ccf44719e64597f54e88aaf
Source noteuspto-grants-2011_06