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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2421531Generated: November 3, 2026

Ethyl 2-chloro-2-(methylsulfanyl)acetate → (3-Iodo-8-methyl quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl ester

https://huagongshe.com/reaction/2421531

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloro-2-(methylsulfanyl)acetateHCID 10877535—
Reactant3-Iodo-8-methyl-quinolin-6-olHCID 66717817—
Product(3-Iodo-8-methyl quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl esterHCID 67214415—

Reaction Steps

In a similar procedure to Stage 2, Step 1 of Example 5, 3-iodo-8-methyl-quinolin-6-ol, was reacted with chloro-methylsulfanyl-acetic acid ethyl ester to give (3-iodo-8-methyl quinolin-6-yloxy)-methylsulfanyl-acetic acid ethyl ester as a yellow coloured solid (MH+ 418).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07956188B2
Source datasetuspto-grants-2011_06
ORD IDord-72415bfdade24819ac9d0187fe59656b
Source noteuspto-grants-2011_06