Sodium Hydroxide → 4-Benzylbenzoic acid

HRID 2421600Notes

Reaction equation

HRID 2421600 reaction equation
[C:1]([C:9]1[CH:17]=[CH:16][C:12]([C:13]([OH:15])=[O:14])=[CH:11][CH:10]=1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[Na+].O.NN>>[C:2]1([CH2:1][C:9]2[CH:10]=[CH:11][C:12]([C:13]([OH:15])=[O:14])=[CH:16][CH:17]=2)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 691474-Benzoylbenzoic acid

Product 1

HCID 1364294-Benzylbenzoic acid

Procedure

4-Phenylmethylbenzoic acid was prepared according to the method of Van Herwijnen et. al., 2001. 4-Benzoylbenzoic acid (452 mg, 2 mmol), powdered NaOH (350 mg), hydrazine hydrate (0.35 mL) and tri(ethylene glycol) (15 mL) were stirred at 190° C. for four hours.

Sources & evidence

ORD record
ord-6992489bb5ce44aca45248a765fd318e
Source dataset
uspto-grants-2011_06
Patent number
US07956216B2

Reaction notes

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