(1,1'-Biphenyl)-3-carboxylic acid → HCID 67214257, compound

Participants

Reaction Steps

Using Preparation Method 1, 3-phenylbenzoic acid was reacted with (2-cyclopropyl)ethylamine. The resulting reaction mixture was purified using SiO2 with CH2Cl2 100%. A white crystalline solid was obtained (69%). NMR 1H (ppm, CDCl3): 7.97 (s, 1H), 7.69 (d, J3=7.7 Hz, 2H), 7.60 (d, J3=7.2 Hz, 2H), 7.51-7.33 (m, 4H), 6.29 (br. s., 1H), 3.60-3.53 (m, 2H), 1.54 (quart., J3=7.0 Hz, 2H), 0.78-0.67 (m, 1H), 0.52-0.46 (m, 2H), 0.14-0.06 (m, 2H).

Provenance & Evidence