Benzylamine → HCID 67214399, compound

Participants

Reaction Steps

Using preparation method 1, 94B (131 mg, 0.74 mmol) was reacted with benzylamine (120 μL, 118 mg, 1.1 mmol). Purification by flash chromatography on SiO2 using CH2Cl2/hexanes 50:50 then CH2Cl2 100% afforded white crystals (1.60 mg, 81%). NMR 1H (ppm, CDCl3): 7.58-7.54 (m, 2H), 7.36-7.24 (m, 7H), 6.35 (br. s, 1H), 4.64 (d, J3=5.7 Hz, 2H), 2.50 (d, J3=7.2 Hz, 2H), 1.92-1.82 (m, 1H), 0.88 (t, J3=6.6 Hz, 6H).

Provenance & Evidence