Methanol → HCID 67241392, compound

HRID 2421840Notes

Reaction equation

HRID 2421840 reaction equation
[Cl:1][CH2:2][CH2:3][S:4][C:5]1[CH:13]=[CH:12][C:8]([C:9](Cl)=[O:10])=[CH:7][C:6]=1[N+:14]([O-:16])=[O:15].C(N(CC)CC)C.[CH3:24][OH:25]>>[Cl:1][CH2:2][CH2:3][S:4][C:5]1[CH:13]=[CH:12][C:8]([C:9]([O:25][CH3:24])=[O:10])=[CH:7][C:6]=1[N+:14]([O-:16])=[O:15]

Participants

4

Reactant 3

HCID 887MethanolHCID 8471TriethylamineHCID 86628742HCID 86628742, compound

Product 1

HCID 67241392HCID 67241392, compound

Procedure

To a solution of 4-(2-chloroethylthio)-3-nitrobenzoyl chloride (22 mg, 0.080 mmol) in MeOH (5 mL) was added triethylamine (0.112 mL, 0.800 mmol). The reaction mixture was allowed to stir for 1 h. TLC analysis of the reaction mixture indicated consumption of starting material. The reaction was concentrated under reduced pressure to provide methyl 4-(2-chloroethylthio)-3-nitrobenzoate (22 mg, 0.080 mmol) as a crude semi-solid, which was used without further purification.

Workup

  1. customconsumption of starting material
  2. concentrationThe reaction was concentrated under reduced pressure

Sources & evidence

ORD record
ord-f57eabee985f4a99bf32e248a5c1bdc5
Source dataset
uspto-grants-2011_06
Patent number
US07960376B2

Reaction notes

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