1,2-Dichloroethane → HCID 86628743, compound

HRID 2421844Notes

Reaction equation

HRID 2421844 reaction equation
OC[CH2:3][C:4](C)([S:6][C:7]1[CH:15]=[CH:14][C:10]([C:11](O)=[O:12])=[CH:9][C:8]=1[N+:16]([O-:18])=[O:17])[CH3:5].S(Cl)([Cl:22])=O.Cl[CH2:25][CH2:26][Cl:27]>>[Cl:27][CH2:26][CH2:25][C:4]([CH3:5])([S:6][C:7]1[CH:15]=[CH:14][C:10]([C:11]([Cl:22])=[O:12])=[CH:9][C:8]=1[N+:16]([O-:18])=[O:17])[CH3:3]

Participants

4

Reactant 3

HCID 111,2-DichloroethaneHCID 24386Thionyl ChlorideHCID 672422364-(4-Hydroxy-2-methylbutan-2-ylthio)-3-nitrobenzoic acid

Product 1

HCID 86628743HCID 86628743, compound

Conditions

Temperature
70 °C

Procedure

To a solution of 4-(4-hydroxy-2-methylbutan-2-ylthio)-3-nitrobenzoic acid (3.08 g, 10.8 mmol) in DCE (50 mL) was added thionyl chloride (2.365 mL, 32.4 mmol). The reaction was heated to 70° C. and stirred at that temperature for 1 hour. The solvent was removed under reduced pressure and the resulting oil was used without further purification.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customthe resulting oil was used without further purification

Sources & evidence

ORD record
ord-165c1f378e0b4025b2810b2a2be1a672
Source dataset
uspto-grants-2011_06
Patent number
US07960376B2

Reaction notes

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