HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)piperazine → HCID 58834858, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)piperazine | HCID 75260 | — |
| Reactant | 4-Fluoro-3-(trifluoromethyl)phenyl isocyanate | HCID 2733383 | — |
| Reactant | HCID 11826263 | HCID 11826263 | — |
| Product | HCID 58834858 | HCID 58834858 | — |
Reaction Steps
Starting with 150 mg (0.34 mmol) of the iminophosphorane from Example 3A, 74 mg (0.34 mmol) of 4-fluoro-3-(trifluoromethyl)phenyl isocyanate and 61 mg (0.34 mmol) of N-(4-fluorophenyl)piperazine, the general procedure [E] and chromatographic purification (method 2) give 111 mg (54% of theory) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960387B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-2430be76b1f14003935d7f8e8f232c94 |
| Source note | uspto-grants-2011_06 |