HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86668978, compound → HCID 86668979, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86668978 | HCID 86668978 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86668979 | HCID 86668979 | 66% |
Reaction Steps
To a stirred solution of (E)-ethyl 4,4-dimethoxy-2-methylbut-2-enoate (1.32 g, 7.01 mmol) in EtOAc (30 mL) was added PtO2 (51 mg, 0.22 mmol). The slurry was hydrogenated over night. Filtration trough celite, concentration and purification using silica gel (CH2Cl2-Et2O 1:0 to 0:1) afforded ethyl 4,4-dimethoxy-2-methylbutanoate (0.88 g, 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653112B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-1ca02aa2d29944e0a6636bc4fd4f76ea |
| Source note | uspto-grants-2014_02 |