HCID 58248072, compound → HCID 24762209, compound

Participants

Reaction Conditions

Reaction Steps

The title compound was prepared from (2R)-2-[(5-{[(1S)-1-(5-chloropyridin-2-yl)ethyl]thio}-2-methoxy[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentan-1-ol from the previous step using General method D except that the reaction mixture was stirred at 50° C. for 2.5 h and then at room temperature over night. After complete reaction the reaction mixture was diluted with Brine and extracted with DCM (three times). The combined organic extracts were dried over sodium sulphate and concentrated in vacuo.

Provenance & Evidence