反应详情

25% Aqueous ammonia (30 mL) was added to methyl 4-hydroxybenzenepropanoate (1.5 g, 8.3 mmol), and the mixture was stirred at room temperature for 15 hrs. Dil. hydrochloric acid was added to the reaction mixture, and the mixture was extracted with ethyl acetate. The extract was washed with water and concentrated under reduced pressure. The residue was recrystallized from ethyl acetate-hexane to give the title compound (0.43 g, yield 31%).

1. extractionthe mixture was extracted with ethyl acetate
2. washThe extract was washed with water
3. concentrationconcentrated under reduced pressure
4. customThe residue was recrystallized from ethyl acetate-hexane