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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2422266Generated: November 1, 2026

1-Bromo-2,6-difluorobenzene → 2',6'-Difluoro[1,1'-biphenyl]-3-carbaldehyde

https://huagongshe.com/reaction/2422266

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2,6-difluorobenzeneHCID 123557—
Reactant3-Formylphenylboronic acidHCID 2734356—
Product2',6'-Difluoro[1,1'-biphenyl]-3-carbaldehydeHCID 23082705—

Reaction Steps

The title compound was synthesized in the same manner as in Reference Example 206 from 1,3-difluoro-2-bromobenzene and 3-formylphenylboronic acid. colorless oil (3.0 g, yield 93%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960369B2
Source datasetuspto-grants-2011_06
ORD IDord-9310d1e384494abbb91c9771b83abd47
Source noteuspto-grants-2011_06