1-Bromo-2,6-difluorobenzene → 2',6'-Difluoro[1,1'-biphenyl]-3-carbaldehyde

HRID 2422266Notes

Reaction equation

HRID 2422266 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1Br.[CH:10]([C:12]1[CH:13]=[C:14](B(O)O)[CH:15]=[CH:16][CH:17]=1)=[O:11]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[C:16]1[CH:15]=[CH:14][CH:13]=[C:12]([CH:10]=[O:11])[CH:17]=1

Participants

3

Reactant 2

HCID 1235571-Bromo-2,6-difluorobenzeneHCID 27343563-Formylphenylboronic acid

Product 1

HCID 230827052',6'-Difluoro[1,1'-biphenyl]-3-carbaldehyde

Procedure

The title compound was synthesized in the same manner as in Reference Example 206 from 1,3-difluoro-2-bromobenzene and 3-formylphenylboronic acid. colorless oil (3.0 g, yield 93%).

Sources & evidence

ORD record
ord-9310d1e384494abbb91c9771b83abd47
Source dataset
uspto-grants-2011_06
Patent number
US07960369B2

Reaction notes

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