反应详情

3′-[4-(2-tert-Butoxycarbonylethyl)phenoxymethyl]biphenyl-2-carboxylic acid (0.15 g, 0.35 mmol) was dissolved in trifluoroacetic acid (3 mL), and the mixture was stirred at room temperature for 1 hr. The reaction mixture was concentrated, and the residue was purified by silica gel column chromatography (hexane/ethyl acetate=1/2-ethyl acetate) to give the title compound (21 mg, yield 16%) as a colorless powder. MS (APCI−): 375 (M−H).

1. concentrationThe reaction mixture was concentrated
2. customthe residue was purified by silica gel column chromatography (hexane/ethyl acetate=1/2-ethyl acetate)