反应详情

温度

150 °C

1.0 g (6.4 mmol) 1-(6-chloropyridin-3-yl)-N-methylmethanamine [for preparation see EP 0 556 684-A1] are initially introduced into 1.5 ml (1.6 g, 31.9 mmol) hydrazine hydrate and the mixture is stirred at the boiling point at a bath temperature of 150° C. for 12 h. The cooled reaction solution is concentrated and the residue is dried in vacuo. 1.1 g of the title compound, which is employed without further purification, are obtained.

1. customThe cooled reaction solution
2. concentrationis concentrated
3. customthe residue is dried in vacuo
4. custom1.1 g of the title compound, which is employed without further purification
5. customare obtained