反应详情

温度

15 °C

1.7 ml (1.7 g, 34.0 mmol) hydrazine hydrate are added to 2.0 g (8.5 mmol) 2,5-bis-(methylsulfonyl)pyridine [Woods et al., J. Heterocycl. Chem. 1984, 21, 97-101] in 15 ml ethanol and the mixture is stirred under reflux for 4 h. For working up, the reaction solution is cooled to 15° C., the solid which has precipitated out is filtered off, the residue on the filter is washed with ethanol and diethyl ether and the product is dried in vacuo.

1. temperatureunder reflux for 4 h
2. customthe solid which has precipitated out
3. filtrationis filtered off
4. washthe residue on the filter is washed with ethanol and diethyl ether
5. customthe product is dried in vacuo