反应详情

9.3 ml (9.5 g, 190.2 mmol) hydrazine hydrate are added to a solution of 1.8 g (9.5 mmol) 5-bromo-2-chloropyridine in 25 ml ethanol at RT, while stirring, and the mixture is then stirred at 90° C. for 46 h. After concentration of the reaction mixture in vacuo, the residue is stirred in water and the solid is filtered off, washed with water and diethyl ether and dried in vacuo.

1. stirringthe mixture is then stirred at 90° C. for 46 h
2. filtrationthe solid is filtered off
3. washwashed with water and diethyl ether
4. customdried in vacuo