反应详情

A mixture of 2.0 g (13.8 mmol) of the compound from Example 7A and 4.3 g (27.7 mmol) 4-pyrrolidin-1-ylpyridine is stirred in 20 ml water at 100° C. for 16 h. The solid which has precipitated out is filtered off, washed first with ethanol and then with diethyl ether and dried in vacuo.

1. customThe solid which has precipitated out
2. filtrationis filtered off
3. washwashed first with ethanol
4. dry with materialwith diethyl ether and dried in vacuo