Methylamine → HCID 11596764, compound

HRID 2422590Notes

Reaction equation

HRID 2422590 reaction equation
[NH2:1][C:2]1[C:7]([C:8]([OH:10])=O)=[CH:6][C:5]([Cl:11])=[N:4][CH:3]=1.[CH3:12][NH2:13].[N:14]1([CH2:20][CH2:21][CH2:22][O:23][C:24]2[CH:31]=[CH:30][C:27]([CH:28]=O)=[CH:26][CH:25]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[Cl:11][C:5]1[N:4]=[CH:3][C:2]2[N:1]=[C:28]([C:27]3[CH:30]=[CH:31][C:24]([O:23][CH2:22][CH2:21][CH2:20][N:14]4[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]4)=[CH:25][CH:26]=3)[N:13]([CH3:12])[C:8](=[O:10])[C:7]=2[CH:6]=1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 27663244-(3-Piperidin-1-ylpropoxy)benzaldehydeHCID 227367915-Amino-2-chloro-isonicotinic acid

Product 1

HCID 11596764HCID 11596764, compound

Procedure

The entitled compound was obtained according to the method of Example 15 but starting from 5-amino-2-chloroisonicotinic acid, methylamine and 4-(3-piperidin-1-ylpropoxy)benzaldehyde.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-d36df018820f4f0e9514028ddfbfca6c
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

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