HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 2-[4-(1-Cyclopentyl-4-piperidinyloxy)phenyl]-3-methylpyrido[2,3-d]-pyrimidin-4(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2-Aminonicotinic acid | HCID 72930 | — |
| Reactant | 4-[(1-Cyclopentyl-4-piperidinyl)oxy]benzaldehyde | HCID 86624460 | — |
| Product | 2-[4-(1-Cyclopentyl-4-piperidinyloxy)phenyl]-3-methylpyrido[2,3-d]-pyrimidin-4(3H)-one | HCID 11531530 | — |
Reaction Steps
The entitled compound was obtained according to the method of Example 15 but starting from 2-aminonicotinic acid, methylamine and 4-[(1-cyclopentyl-4-piperidinyl)oxy]benzaldehyde. The obtained compound was recrystallized from diethyl ether to give a pale yellow acicular crystal (m.p. 175.0-177.2° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960394B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-a1d5c9fda8ec46bdbbb4ec086fa42c81 |
| Source note | uspto-grants-2011_06 |