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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2422600Generated: October 26, 2026

Methylamine → 6-Chloro-2-{4-[(1-cyclopentylpiperidin-4-yl)oxy]phenyl}-3-methylpyrido[3,4-d]pyrimidin-4(3H)-one

https://huagongshe.com/reaction/2422600

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant5-Amino-2-chloro-isonicotinic acidHCID 22736791—
Reactant4-[(1-Cyclopentyl-4-piperidinyl)oxy]benzaldehydeHCID 86624460—
Product6-Chloro-2-{4-[(1-cyclopentylpiperidin-4-yl)oxy]phenyl}-3-methylpyrido[3,4-d]pyrimidin-4(3H)-oneHCID 11704819—

Reaction Steps

The entitled compound was obtained according to the method of Example 15 but starting from 5-amino-2-chloroisonicotinic acid, methylamine and 4-[(1-cyclopentyl-4-piperidinyl)oxy]benzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960394B2
Source datasetuspto-grants-2011_06
ORD IDord-ff678b8d2f144670a8d7826251978720
Source noteuspto-grants-2011_06