Methylamine → HCID 11502838, compound

HRID 2422603Notes

Reaction equation

HRID 2422603 reaction equation
[NH2:1][C:2]1[C:7]([C:8]([OH:10])=O)=[CH:6][C:5]([Cl:11])=[N:4][CH:3]=1.[CH3:12][NH2:13].[CH3:14][O:15][C:16]1[CH:23]=[C:22]([O:24][CH2:25][CH2:26][CH2:27][N:28]2[CH2:32][CH2:31][CH2:30][CH2:29]2)[CH:21]=[CH:20][C:17]=1[CH:18]=O>>[Cl:11][C:5]1[N:4]=[CH:3][C:2]2[N:1]=[C:18]([C:17]3[CH:20]=[CH:21][C:22]([O:24][CH2:25][CH2:26][CH2:27][N:28]4[CH2:32][CH2:31][CH2:30][CH2:29]4)=[CH:23][C:16]=3[O:15][CH3:14])[N:13]([CH3:12])[C:8](=[O:10])[C:7]=2[CH:6]=1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 227367915-Amino-2-chloro-isonicotinic acidHCID 86084807HCID 86084807, compound

Product 1

HCID 11502838HCID 11502838, compound

Procedure

The entitled compound was obtained according to the method of Example 15 but starting from 5-amino-2-chloroisonicotinic acid, methylamine and 2-methoxy-4-(3-pyrrolidin-1-ylpropoxy)benzaldehyde.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-871780dee69349dcbdcefd9027b62839
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

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