Methylamine → HCID 44563137, compound

HRID 2422608Notes

Reaction equation

HRID 2422608 reaction equation
[NH2:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:15][NH2:16].[CH:17]1([N:21]2[CH2:26][CH2:25][CH:24]([O:27][C:28]3[CH:35]=[CH:34][C:31]([CH:32]=O)=[CH:30][CH:29]=3)[CH2:23][CH2:22]2)[CH2:20][CH2:19][CH2:18]1>>[CH:17]1([N:21]2[CH2:26][CH2:25][CH:24]([O:27][C:28]3[CH:35]=[CH:34][C:31]([C:32]4[N:16]([CH3:15])[C:4](=[O:6])[C:3]5[C:2](=[C:10]([C:11]([F:14])([F:13])[F:12])[CH:9]=[CH:8][CH:7]=5)[N:1]=4)=[CH:30][CH:29]=3)[CH2:23][CH2:22]2)[CH2:20][CH2:19][CH2:18]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 6045692-Amino-3-(trifluoromethyl)benzoic acidHCID 866244614-[(1-Cyclobutyl-4-piperidinyl)oxy]benzaldehyde

Product 1

HCID 44563137HCID 44563137, compound

Procedure

The entitled compound was obtained according to the method of Example 15 but starting from 2-amino-3-trifluoromethylbenzoic acid, methylamine and 4-[(1-cyclobutyl-4-piperidinyl)oxy]benzaldehyde.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-438a6ef34fc0458cb993e9b193bcdadc
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

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