Methylamine → HCID 11655077, compound

HRID 2422614Notes

Reaction equation

HRID 2422614 reaction equation
[NH2:1][C:2]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:12][NH2:13].[CH3:14][O:15][C:16]1[CH:23]=[C:22]([O:24][CH2:25][CH2:26][CH2:27][N:28]2[CH2:33][CH2:32][CH2:31][C@H:30]([CH3:34])[CH2:29]2)[CH:21]=[CH:20][C:17]=1[CH:18]=O>>[F:11][C:10]1[CH:9]=[CH:8][CH:7]=[C:3]2[C:2]=1[N:1]=[C:18]([C:17]1[CH:20]=[CH:21][C:22]([O:24][CH2:25][CH2:26][CH2:27][N:28]3[CH2:33][CH2:32][CH2:31][C@H:30]([CH3:34])[CH2:29]3)=[CH:23][C:16]=1[O:15][CH3:14])[N:13]([CH3:12])[C:4]2=[O:6]

Participants

4

Reactant 3

HCID 6329MethylamineHCID 5864082-Amino-3-fluorobenzoic acidHCID 86624464HCID 86624464, compound

Product 1

HCID 11655077HCID 11655077, compound

Procedure

The entitled compound was obtained according to the method of Example 15 but starting from 2-amino-3-fluorobenzoic acid, methylamine and 2-methoxy-4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}benzaldehyde.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-2a0fb88362834784aaa74bdde6b0d78f
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

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