Methylamine → HCID 11567952, compound
Reaction equation
[NH2:1][C:2]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:13][NH2:14].[CH:15]1([N:19]2[CH2:24][CH2:23][CH:22]([O:25][C:26]3[CH:33]=[CH:32][C:29]([CH:30]=O)=[CH:28][CH:27]=3)[CH2:21][CH2:20]2)[CH2:18][CH2:17][CH2:16]1>>[CH:15]1([N:19]2[CH2:24][CH2:23][CH:22]([O:25][C:26]3[CH:33]=[CH:32][C:29]([C:30]4[N:14]([CH3:13])[C:4](=[O:6])[C:3]5[C:2](=[CH:10][C:9]([O:11][CH3:12])=[CH:8][CH:7]=5)[N:1]=4)=[CH:28][CH:27]=3)[CH2:21][CH2:20]2)[CH2:18][CH2:17][CH2:16]1Participants
4
Procedure
The entitled compound was obtained according to the method of Example 15 but starting from 2-amino-4-methoxybenzoic acid, methylamine and 4-[(1-cyclobutyl-4-piperidinyl)oxy]benzaldehyde.
Workup
- customThe entitled compound was obtained
Sources & evidence
- ORD record
- ord-6d7ebd1e3fd747bfbbe003cb68164107
- Source dataset
- uspto-grants-2011_06
- Patent number
- US07960394B2
Reaction notes
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