Methylamine → HCID 11633142, compound

HRID 2422628Notes

Reaction equation

HRID 2422628 reaction equation
[NH2:1][C:2]1[C:3]([C:10]([OH:12])=O)=[N:4][CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH3:13][NH2:14].[CH:15]1([N:19]2[CH2:24][CH2:23][CH:22]([O:25][C:26]3[CH:33]=[CH:32][C:29]([CH:30]=O)=[CH:28][CH:27]=3)[CH2:21][CH2:20]2)[CH2:18][CH2:17][CH2:16]1>>[CH:15]1([N:19]2[CH2:24][CH2:23][CH:22]([O:25][C:26]3[CH:33]=[CH:32][C:29]([C:30]4[N:14]([CH3:13])[C:10](=[O:12])[C:3]5[N:4]=[CH:5][CH:6]=[C:7]([O:8][CH3:9])[C:2]=5[N:1]=4)=[CH:28][CH:27]=3)[CH2:21][CH2:20]2)[CH2:18][CH2:17][CH2:16]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 58523918HCID 58523918, compoundHCID 866244614-[(1-Cyclobutyl-4-piperidinyl)oxy]benzaldehyde

Product 1

HCID 11633142HCID 11633142, compound

Procedure

The entitled compound was obtained as a pale yellow solid (m.p. 182.2-205.2° C.), according to the method of Example 15 but starting from 3-amino-4-methoxypyridin-2-carboxylic acid, methylamine and 4-[(1-cyclobutyl-4-piperidinyl)oxy]benzaldehyde.

Sources & evidence

ORD record
ord-f624febc67a84fafba6183bdff66fdcc
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

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