Methylamine → HCID 67245927, compound

HRID 2422643Notes

Reaction equation

HRID 2422643 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-])=O)=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:14][NH2:15].[N:16]1([CH2:21][CH2:22][CH2:23][O:24][C:25]2[CH:32]=[CH:31][C:28]([CH:29]=O)=[CH:27][CH:26]=2)[CH2:20][CH2:19][CH2:18][CH2:17]1.[CH3:33][S:34](Cl)(=[O:36])=[O:35]>>[CH3:14][N:15]1[C:4](=[O:6])[C:3]2[C:2](=[CH:10][CH:9]=[C:8]([NH:11][S:34]([CH3:33])(=[O:36])=[O:35])[CH:7]=2)[N:1]=[C:29]1[C:28]1[CH:31]=[CH:32][C:25]([O:24][CH2:23][CH2:22][CH2:21][N:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:26][CH:27]=1

Participants

5

Reactant 4

HCID 6329MethylamineHCID 120322-Amino-5-nitrobenzoic acidHCID 31297Methanesulfonyl chlorideHCID 116515734-(3-Pyrrolidin-1-ylpropoxy)benzaldehyde

Product 1

HCID 67245927HCID 67245927, compound

Procedure

The entitled compound was obtained according to the method of Example 70 but starting from 2-amino-5-nitrobenzoic acid, methylamine and 4-(3-pyrrolidin-1-ylpropoxy)benzaldehyde and methanesulfonyl chloride.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-41c0b6471e0540ff98bf229e9b723c93
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

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