Methylamine → HCID 67243990, compound

HRID 2422644Notes

Reaction equation

HRID 2422644 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-])=O)=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:14][NH2:15].[N:16]1([CH2:22][CH2:23][CH2:24][O:25][C:26]2[CH:33]=[CH:32][C:29]([CH:30]=O)=[CH:28][CH:27]=2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1.[C:34](Cl)(=[O:36])[CH3:35]>>[C:34]([NH:11][C:8]1[CH:7]=[C:3]2[C:2](=[CH:10][CH:9]=1)[N:1]=[C:30]([C:29]1[CH:32]=[CH:33][C:26]([O:25][CH2:24][CH2:23][CH2:22][N:16]3[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]3)=[CH:27][CH:28]=1)[N:15]([CH3:14])[C:4]2=[O:6])(=[O:36])[CH3:35]

Participants

5

Reactant 4

HCID 6329MethylamineHCID 6367Acetyl chlorideHCID 120322-Amino-5-nitrobenzoic acidHCID 27663244-(3-Piperidin-1-ylpropoxy)benzaldehyde

Product 1

HCID 67243990HCID 67243990, compound

Procedure

The entitled compound was obtained according to the method of Example 70 but starting from 2-amino-5-nitrobenzoic acid, methylamine and 4-(3-piperidin-1-ylpropoxy)benzaldehyde and acetyl chloride.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-fe90f0fbf15b46bdb54a2aff0ec8cf69
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

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