Anthranilic Acid → HCID 11567113, compound
Reaction equation
[C:1]([OH:10])(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[CH3:11][NH2:12].[F:13][C:14]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][C:15]=1[CH:16]=O.[Br-].BrCC[CH2:28][NH+:29]1[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1>>[CH3:11][N:12]1[C:1](=[O:10])[C:2]2[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:4]=[C:16]1[C:15]1[CH:18]=[CH:19][C:20]([O:22][CH2:23][CH2:33][CH2:34][N:29]2[CH2:28][CH2:32][CH2:31][CH2:30]2)=[CH:21][C:14]=1[F:13]Participants
5
Procedure
The entitled compound was obtained according to the method of Example 77 but starting from anthranilic acid, methylamine, 2-fluoro-4-methoxybenzaldehyde and 1-(3-bromopropyl)piperidinium bromide.
Workup
- customThe entitled compound was obtained
Sources & evidence
- ORD record
- ord-24dcdd0a557841489e4f506dc62f4d50
- Source dataset
- uspto-grants-2011_06
- Patent number
- US07960394B2
Reaction notes
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