Anthranilic Acid → HCID 67244814, compound

HRID 2422668Notes

Reaction equation

HRID 2422668 reaction equation
[C:1]([OH:10])(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[CH3:11][NH2:12].[F:13][C:14]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][C:15]=1[CH:16]=O.OC1[CH2:30][CH2:29][N:28](C(OC(C)(C)C)=O)[CH2:27][CH2:26]1.[C:38]1(=O)[CH2:42][CH2:41][CH2:40][CH2:39]1>>[CH:38]1([N:28]2[CH2:29][CH2:30][CH:23]([O:22][C:20]3[CH:19]=[CH:18][C:15]([C:16]4[N:12]([CH3:11])[C:1](=[O:10])[C:2]5[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=5)[N:4]=4)=[C:14]([F:13])[CH:21]=3)[CH2:26][CH2:27]2)[CH2:42][CH2:41][CH2:40][CH2:39]1

Participants

6

Reactant 5

HCID 227Anthranilic AcidHCID 6329MethylamineHCID 8452CyclopentanoneHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylateHCID 27348732-Fluoro-4-methoxybenzaldehyde

Product 1

HCID 67244814HCID 67244814, compound

Procedure

The entitled compound was obtained according to the method of Example 85 but using anthranilic acid, methylamine, 2-fluoro-4-methoxybenzaldehyde, tert-butyl 4-hydroxytetrahydro-1(2H)-pyridinecarboxylate, and cyclopentanone.

Workup

  1. customThe entitled compound was obtained

Sources & evidence

ORD record
ord-fec84a2113e046ec86b497fe3cf454f1
Source dataset
uspto-grants-2011_06
Patent number
US07960394B2

Reaction notes

Loading…