反应详情

温度

100 °C

5-Bromo-2-cyano-3-nitropyridine (500 mg, 2.19 mmol) was dissolved in concentrated sulfuric acid (1 mL), and stirred at 100° C. for 2 hours. After cooled to 0° C., water was added thereto, and stirred at that temperature. The resulting pale gray solid was taken out through filtration and dried to obtain the intended compound (447 mg, 83%).

1. temperatureAfter cooled to 0° C.
2. stirringstirred at that temperature
3. filtrationThe resulting pale gray solid was taken out through filtration
4. customdried