HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2422682Generated: October 26, 2026
Water → 5-Bromo-3-nitropyridine-2-carboxamide
https://huagongshe.com/reaction/2422682
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 5-Bromo-3-nitropyridine-2-carbonitrile | HCID 2769698 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 5-Bromo-3-nitropyridine-2-carboxamide | HCID 67244466 | 83% |
Reaction Steps
5-Bromo-2-cyano-3-nitropyridine (500 mg, 2.19 mmol) was dissolved in concentrated sulfuric acid (1 mL), and stirred at 100° C. for 2 hours. After cooled to 0° C., water was added thereto, and stirred at that temperature. The resulting pale gray solid was taken out through filtration and dried to obtain the intended compound (447 mg, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07960394B2 |
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| Source dataset | uspto-grants-2011_06 |
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| ORD ID | ord-9df5c7c357614e7bab51d22418ce2edd |
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| Source note | uspto-grants-2011_06 |
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