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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2422861Generated: November 2, 2026

1-Methyl-3-(trifluoromethyl)-1H-pyrazole-4-sulfonyl chloride → 1-Methyl-3-trifluoromethyl-1H-pyrazole-4-sulfonic-acid (5'-fluoro-2,2'-dimethoxy-biphenyl-4-ylmethyl)-amide

https://huagongshe.com/reaction/2422861

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-3-(trifluoromethyl)-1H-pyrazole-4-sulfonyl chlorideHCID 2794561—
ReactantHCID 24768914HCID 24768914—
Product1-Methyl-3-trifluoromethyl-1H-pyrazole-4-sulfonic-acid (5'-fluoro-2,2'-dimethoxy-biphenyl-4-ylmethyl)-amideHCID 24769077—

Reaction Steps

Prepared in a similar manner to N-(5′-fluoro-2,2′-dimethoxy-biphenyl-4ylmethyl)-4-methoxy-benzenesulfonamide (Example 6) using 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-sulfonyl chloride instead of 4-methoxybenzene sulfonyl chloride. Title compound: MS (ESI) m/z: 474.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960365B2
Source datasetuspto-grants-2011_06
ORD IDord-03197f09b1f2478f93a3e8875b475822
Source noteuspto-grants-2011_06