HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)aniline → N-[4-(Trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)aniline | HCID 9964 | — |
| Reactant | 2-Chlorobenzimidazole | HCID 78572 | — |
| Product | N-[4-(Trifluoromethyl)phenyl]-1H-benzimidazol-2-amine | HCID 15604320 | — |
Reaction Steps
The title compound was prepared from 2-chlorobenzimidazole and 4-(trifluoromethyl)aniline by Procedure A. The product was isolated by filtration and preparative LCMS to give the title compound as the free base (white solid, mp 199-200° C.). MS(ES+) m/z 278 ([M+1]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960561B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-7241984eb3f449489a1675537fbcb3dc |
| Source note | uspto-grants-2011_06 |