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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423033Generated: November 1, 2026

2-Chlorobenzimidazole → N-[4-(Trifluoromethoxy)phenyl]-1H-benzimidazol-2-amine

https://huagongshe.com/reaction/2423033

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzimidazoleHCID 78572—
Reactant4-(Trifluoromethoxy)anilineHCID 600848—
ProductN-[4-(Trifluoromethoxy)phenyl]-1H-benzimidazol-2-amineHCID 15604435—

Reaction Steps

The title compound was prepared from 2-chlorobenzimidazole and 4-(trifluoromethoxy)aniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (white solid, mp 250-251° C.). MS(ES+) m/z 294 ([M+1]+, 100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960561B2
Source datasetuspto-grants-2011_06
ORD IDord-b22494bc54b649ff8d526a976a9013fc
Source noteuspto-grants-2011_06