Benzenamine, 3,5-bis(trifluoromethyl)- → N-[3,5-Bis(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine

HRID 2423040Notes

Reaction equation

HRID 2423040 reaction equation
Cl[C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[F:11][C:12]([F:25])([F:24])[C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:19]=1)[NH2:16]>>[N:6]1[C:5]2[CH:7]=[CH:8][CH:9]=[CH:10][C:4]=2[NH:3][C:2]=1[NH:16][C:15]1[CH:17]=[C:18]([C:20]([F:21])([F:22])[F:23])[CH:19]=[C:13]([C:12]([F:11])([F:24])[F:25])[CH:14]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 785722-Chlorobenzimidazole

Product 1

HCID 15604440N-[3,5-Bis(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine

Procedure

The title compound was prepared from 2-chlorobenzimidazole and 3,5-bis(trifluoromethyl)aniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (white solid, mp 245-246° C.). MS(ES+) m/z 346 ([M+1]+, 100).

Workup

  1. customThe product was isolated by filtration

Sources & evidence

ORD record
ord-aff9abfddac04000bfb73b0d6dcded15
Source dataset
uspto-grants-2011_06
Patent number
US07960561B2

Reaction notes

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