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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423040Generated: November 1, 2026

Benzenamine, 3,5-bis(trifluoromethyl)- → N-[3,5-Bis(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine

https://huagongshe.com/reaction/2423040

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant2-ChlorobenzimidazoleHCID 78572—
ProductN-[3,5-Bis(trifluoromethyl)phenyl]-1H-benzimidazol-2-amineHCID 15604440—

Reaction Steps

The title compound was prepared from 2-chlorobenzimidazole and 3,5-bis(trifluoromethyl)aniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (white solid, mp 245-246° C.). MS(ES+) m/z 346 ([M+1]+, 100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960561B2
Source datasetuspto-grants-2011_06
ORD IDord-aff9abfddac04000bfb73b0d6dcded15
Source noteuspto-grants-2011_06