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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423041Generated: November 1, 2026

3-Chloro-4-fluoroaniline → N-(3-Chloro-4-fluorophenyl)-1H-benzimidazol-2-amine

https://huagongshe.com/reaction/2423041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-fluoroanilineHCID 9708—
Reactant2-ChlorobenzimidazoleHCID 78572—
ProductN-(3-Chloro-4-fluorophenyl)-1H-benzimidazol-2-amineHCID 15604441—

Reaction Steps

The title compound was prepared from 2-chlorobenzimidazole and 3-chloro-4-fluoroaniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (white solid, mp 306-307° C.). MS(ES+) m/z 262 ([M+1]+, 100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960561B2
Source datasetuspto-grants-2011_06
ORD IDord-a7a735dab62b4259a74657e74578362b
Source noteuspto-grants-2011_06