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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423043Generated: October 27, 2026

4-Bromo-3-(trifluoromethyl)aniline → N-[4-Bromo-3-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine

https://huagongshe.com/reaction/2423043

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-3-(trifluoromethyl)anilineHCID 67852—
Reactant2-ChlorobenzimidazoleHCID 78572—
ProductN-[4-Bromo-3-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amineHCID 15602779—

Reaction Steps

The title compound was prepared from 2-chlorobenzimidazole and 4-bromo-3-(trifluoromethyl)aniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (white solid, mp 262-264° C.). MS(ES+) m/z 356 (M+, 100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960561B2
Source datasetuspto-grants-2011_06
ORD IDord-e1994f61d11b4a96955b11ea1adf9269
Source noteuspto-grants-2011_06