HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzimidazole → N-[3-Fluoro-5-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzimidazole | HCID 78572 | — |
| Reactant | 3-Amino-5-fluorobenzotrifluoride | HCID 2735913 | — |
| Product | N-[3-Fluoro-5-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine | HCID 15602781 | — |
Reaction Steps
The title compound was prepared from 2-chlorobenzimidazole and 3-fluoro-5-(trifluoromethyl)aniline by Procedure A. The product was isolated by filtration to give the title compound as a hydrochloride salt (white solid, mp 263-265° C.). MS(ES+) m/z 296 ([M+1]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960561B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-ef9e6539457e4c479073b2ab66ebaea3 |
| Source note | uspto-grants-2011_06 |