HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,4-Trifluoroaniline → N-(2,3,4-Trifluorophenyl)-1H-benzimidazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,4-Trifluoroaniline | HCID 77468 | — |
| Reactant | 2-Chlorobenzimidazole | HCID 78572 | — |
| Product | N-(2,3,4-Trifluorophenyl)-1H-benzimidazol-2-amine | HCID 15602784 | — |
Reaction Steps
The title compound was prepared from 2-chlorobenzimidazole and 2,3,4-trifluoroaniline by Procedure A. The product was isolated by filtration and preparative LCMS to give the title compound as the free base (white solid, mp 182-183° C.). MS(ES+) m/z 264 ([M+1]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960561B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-debaacbeaa3341f486c04cd22741d8e3 |
| Source note | uspto-grants-2011_06 |