Thionyl Chloride → HCID 57780641, compound

HRID 2423239Notes

Reaction equation

HRID 2423239 reaction equation
S(Cl)([Cl:3])=O.[Cl:5][S:6]([C:9]1[C:10]([O:18][CH3:19])=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12](O)=[O:13])(=[O:8])=[O:7]>CN(C)C=O>[Cl:5][S:6]([C:9]1[C:10]([O:18][CH3:19])=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12]([Cl:3])=[O:13])(=[O:8])=[O:7]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 86632595HCID 86632595, compound

Product 1

HCID 57780641HCID 57780641, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Conditions

Temperature
60 °C

Procedure

Three drops of N,N-dimethylformamide were added to a thionyl chloride (4.37 mL) suspension of 3-(chlorosulfonyl)-2-methoxybenzoic acid (3.00 g), followed by stirring at 60° C. for 2 hours. The solvent was evaporated, and this was azeotroped with toluene to obtain 3-(chlorosulfonyl)-2-methoxybenzoyl chloride (3.22 g).

Workup

  1. customThe solvent was evaporated
  2. customthis was azeotroped with toluene

Sources & evidence

ORD record
ord-9d7e4f6243114737a2c4ee4a30383fb9
Source dataset
uspto-grants-2011_06
Patent number
US07960562B2

Reaction notes

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