HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(3-methoxy-4-(5-nitroquinolin-6-yloxy)phenyl)acetate → Ethyl 2-(4-(5-aminoquinolin-6-yloxy)-3-methoxyphenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(3-methoxy-4-(5-nitroquinolin-6-yloxy)phenyl)acetate | HCID 59864865 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-(4-(5-aminoquinolin-6-yloxy)-3-methoxyphenyl)acetate | HCID 59864773 | — |
Reaction Steps
Pd/C (30 mg) was added to 24.3 (310 mg) in EtOH (10 mL). The mixture was stirred under hydrogen at room temperature for 6 h. The catalyst was removed by filtration through celite. The filtrate was concentrated under vacuum to give 24.4. MS ESI (pos.) m/z: 353.1 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960567B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-c8724ae8dfef40108eebf9c767ea9de2 |
| Source note | uspto-grants-2011_06 |