HCID 59864784, compound → HCID 59864822, compound

HRID 2423320Notes

Reaction equation

HRID 2423320 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:24][C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH:6]=[CH:7][C:8]=1[O:9][C:10]1[C:11]([N+:21]([O-])=O)=[C:12]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[CH:14]=[CH:13]2>CCO.[Pd]>[NH2:21][C:11]1[C:10]([O:9][C:8]2[CH:7]=[CH:6][C:5]([CH2:24][C:25]([O:27][CH2:28][CH3:29])=[O:26])=[CH:4][C:3]=2[O:2][CH3:1])=[CH:19][CH:18]=[C:17]2[C:12]=1[CH:13]=[CH:14][C:15](=[O:20])[NH:16]2

Participants

4

Reactant 1

HCID 59864784HCID 59864784, compound

Product 1

HCID 59864822HCID 59864822, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Pd/C (30 mg) was added to 25.2 (250 mg) in EtOH (15 mL). The mixture was stirred under hydrogen at room temperature for 6 h. The catalyst was removed by filtration through celite. The filtrate was concentrated under vacuum to give 25.3. MS ESI (pos.) m/z: 369.1 (M+H).

Workup

  1. customThe catalyst was removed by filtration through celite
  2. concentrationThe filtrate was concentrated under vacuum

Sources & evidence

ORD record
ord-21d0fa7938b0411a923dee681c029492
Source dataset
uspto-grants-2011_06
Patent number
US07960567B2

Reaction notes

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