反应详情

(2-chloro-5-iodo-4-methanesulfonylamino-benzyl)-carbamic acid isopropyl ester (100 mg, 0.22 mmol) was put into a dried 25 ml of round-bottom flask and dissolved in methylenechloride. To the solution were added 5-6 drops of CF3COOH and stirred for 12 hours. After confirming the completion of the reaction with TLC, the resulting solution was concentrated under reduced pressure using toluene to yield a brown syrup (102.1 mg, 130.48%).

1. customthe completion of the reaction with TLC
2. concentrationthe resulting solution was concentrated under reduced pressure