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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423570Generated: November 2, 2026

4-(2-Amino-2-methylpropoxy)-3-fluorobenzonitrile → 4-(2-Dimethylamino-2-methylpropoxy)-3-fluorobenzaldehyde

https://huagongshe.com/reaction/2423570

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Amino-2-methylpropoxy)-3-fluorobenzonitrileHCID 23087234—
Reactant4-(2-Dimethylamino-2-methylpropoxy)-3-fluorobenzonitrileHCID 23087417—
Product4-(2-Dimethylamino-2-methylpropoxy)-3-fluorobenzaldehydeHCID 23087152—

Reaction Steps

Synthesized from 4-(2-amino-2-methylpropoxy)-3-fluorobenzonitrile according to an analogous synthetic method to Preparation Example 18, 4-(2-dimethylamino-2-methylpropoxy)-3-fluorobenzonitrile (1.4 g) was used according to an analogous synthetic method to Preparation Example 16 to provide the title compound (965 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960412B2
Source datasetuspto-grants-2011_06
ORD IDord-7cc2337730eb4a5fae32ae28a2627444
Source noteuspto-grants-2011_06