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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423573Generated: October 31, 2026

4-Piperidinol, 1-methyl- → HCID 23087228, compound

https://huagongshe.com/reaction/2423573

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Piperidinol, 1-methyl-HCID 66048—
Reactant3,4-DifluorobenzonitrileHCID 587203—
Reactant3-Fluoro-4-(1-methylpiperidin-4-yloxy)benzonitrileHCID 23087412—
ProductHCID 23087228HCID 23087228—

Reaction Steps

Synthesized from 4-hydroxy-1-methylpiperidine and 3,4-difluorobenzonitrile according to an analogous synthetic method to Preparation Example 15, 3-fluoro-4-(1-methylpiperidin-4-yloxy)benzonitrile (1.1 g) was used according to an analogous synthetic method to Preparation Example 16 to provide the title compound (1.1 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960412B2
Source datasetuspto-grants-2011_06
ORD IDord-7da41b010ebd47aab4379e8fc531c776
Source noteuspto-grants-2011_06