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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423588Generated: November 1, 2026

3-Bromoanisole → (2-Bromo-4-methoxyphenyl)[3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl]methanone

https://huagongshe.com/reaction/2423588

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromoanisoleHCID 16971—
Reactant3-Fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochlorideHCID 66626827—
Product(2-Bromo-4-methoxyphenyl)[3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl]methanoneHCID 57934302—

Reaction Steps

Synthesized from 3-bromoanisole (1.1 ml) and 3-fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochloride (3.3 g) according to an analogous synthetic method to Preparation Example 66, the title compound (1.6 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960412B2
Source datasetuspto-grants-2011_06
ORD IDord-01c66621a53e44f0b121ac949f61287c
Source noteuspto-grants-2011_06